In vitro patterns predict clinical effects
نویسندگان
چکیده
منابع مشابه
patterns and variations in native and non-native interlanguage pragmatic rating: effects of rater training, intercultural proficiency, and self-assessment
although there are studies on pragmatic assessment, to date, literature has been almost silent about native and non-native english raters’ criteria for the assessment of efl learners’ pragmatic performance. focusing on this topic, this study pursued four purposes. the first one was to find criteria for rating the speech acts of apology and refusal in l2 by native and non-native english teachers...
15 صفحه اولanalyzing patterns of classroom interaction in efl classrooms in iran
با به کار گیری روش گفتما ن شنا سی در تحقیق حا ضر گفتا ر میا ن آموزگا را ن و زبا ن آموزا ن در کلا سهای زبا ن انگلیسی در ایرا ن مورد بررسی قرار گرفت. ا هداف تحقیق عبا رت بودند از: الف) شنا سا ئی سا ختارهای ارتبا ط گفتا ری میا ن معلمین و زبا ن آموزا ن ب) بررسی تا ثیر نقش جنسیت دبیرا ن و زبا ن آموزان بر سا ختا رهای ارتبا ط گفتا ری میا ن آنها پ) مشخص کردن اینکه آ یا آموزگاران غا لب بر این ارتبا ط گف...
MiRNA expression patterns predict survival in glioblastoma
BACKGROUND In order to define new prognostic subgroups in patients with glioblastoma a miRNA screen (> 1000 miRNAs) from paraffin tissues followed by a bio-mathematical analysis was performed. METHODS 35 glioblastoma patients treated between 7/2005 - 8/2008 at a single institution with surgery and postoperative radio(chemo)therapy were included in this retrospective analysis. For microarray a...
متن کاملIn vitro assays fail to predict in vivo effects of regulatory polymorphisms.
A typical paradigm in the investigation of complex human disease is to assess the effects of cis-regulatory polymorphisms implicated in association studies on transcription in cellular expression systems. Evidence from in vitro transfection studies is often assumed to be sufficient evidence for the in vivo functional importance of a polymorphism in the context of human disease, even though many...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2006
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd1953